Before CIS Biotech's patented assays, no blood tests were available to detect brain markers of cerebral ischemia. None of the previously available technologies allowed physicians to diagnose or predict ischemic stroke directly and cost-effectively. Now there is a solution!

Based on preclinical and clinical studies, two assays have been created and developed by CIS Biotech, Inc.

1. Gold Dot NR2 Antibody test: The Gold Dot NR2 Antibody assay is a serological enzyme-linked immunosorbent assay (ELISA) for the quantitative determination of antibodies to the NR2 subunit of human NMDA glutamate receptor in serum. The test is intended to be used in conjunction with clinical evaluation and radiological methods for diagnosis of transient ischemic attack (TIA) and ischemic stroke vs stroke-like disorders. The Gold Dot NR2 Antibody ELISA indicates prior isolated or multiple ischemic stroke and increased risk of near-term cerebral ischemic events in patients with preexisting conditions (diabetes, hypertension, atherosclerosis, cardiovascular disorders). The test allows differentiation between ischemic and hemorrhagic stroke. For more information please take a look at the Gold Dot NR2 Antibody test flyer.

2. Gold Dot NR2 Peptide test: The Gold Dot NR2 Peptide test is a magnetic particle-based enzyme-linked immunosorbent assay (ELISA) intended for the quantitative determination of NR2 peptide fragment of NMDA receptors in plasma. The test is intended to be used in conjunction with clinical evaluation and radiological methods for diagnosis of ischemic stroke and transient ischemic attack (TIA). The Gold Dot NR2 Peptide test correlates with acute TIA and ischemic strokes affecting areas of cerebral cortex. The test allows differentiation between acute cerebral ischemic event and hemorrhagic stroke and stroke mimics. For more information please take a look at the Gold Dot NR2 Peptide test flyer.

Both tests have CE mark and can be sold for research use only in the USA.

CIS Biotech, Inc has a CLIA certificate and Georgia State License for Gold Dot NR2 Peptide test and Gold Dot NR2 Antibody test. We can perform the testing at our facility for in and out of state patients if they are referred by authorized physician (the request paperwork will be provided upon your request) and if your state does not have any additional certification requirements for out of state sample shipment and analysis. For further information please browse over to our contact page and fill out the form and we will get back to you as soon as possible. Thank You!.